CYT107 for Kaposi sarcoma in HIV patients with low CD4
Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.
This trial tests an experimental drug (CYT107) that boosts the immune system to help fight Kaposi sarcoma in people with HIV who have a low CD4 count despite good HIV treatment. It aims to see if the drug can improve KS tumors and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have Kaposi sarcoma (KS) confirmed by a biopsy.
- You must be HIV-positive and on effective HIV treatment (ART) for at least 2 months, with a low viral load (100 copies/mL or less).
- Your CD4 cell count must be 350 or lower despite ART.
- You must have at least 5 measurable KS spots on your skin that haven't been treated locally.
- You must be 18 or older and have adequate organ function (e.g., blood counts, liver and kidney function).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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