Study of inherited causes of low puberty hormones
Part of Genetic & congenital, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study looks at families to understand inherited (genetic or family-related) reasons some people have delayed puberty or develop puberty abnormally. It may help doctors better figure out the cause of low sex hormone levels and related hormone problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have puberty that is delayed, too early, or later followed by low sex hormone levels
- OR your clinician suspects an increased risk of hypogonadotropic hypogonadism (low puberty-driving signals from the brain)
- Your sex hormone pattern is consistent with low sex steroids and low or normal “gonadotropins” (measured blood hormone levels)
- You do not have additional pituitary hormone deficiencies beyond the suspected puberty signal issue
- You are not taking medicines that can affect the brain’s puberty hormone signals (such as long-term corticosteroids or continuous opioid use)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how the environment and your body's natural hormones interact. It is for people with reproductive or hormone-related conditions such as low sex hormones (hypogonadism), infertility, early or late puberty, PCOS, or menopause. The researchers will observe participants over time to learn more about these conditions.
This study follows people who may have too much “androgen” (a hormone) to learn what causes it and how it changes over time. You may be followed even if the exact cause is not yet known, and your results may help doctors better understand these conditions.
This study evaluates children (and sometimes relatives) who may have hormone (endocrine) or metabolism-related conditions. It helps doctors better understand these problems by doing a clinical evaluation.
This early study looks at how certain “male-type” hormones and brain signals (measured through hormone patterns during the day and night) work in adolescent girls with high androgen levels. It may help researchers better understand causes like PCOS and related hormone timing differences.
This study follows families from an earlier infant feeding study to better understand what affects when puberty starts. It looks at growth and hormone-related health information to explain differences in pubertal development.
This study looks for new genetic causes of certain “development disorders” that involve hormone problems and how the body develops at puberty. It may help families understand the root cause, which can guide future care and testing.
Hear when a new Genetic Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.