Patient registry for hypophosphatasia (HPP)
Part of Genetic & congenital, Hormones & metabolism clinical trials.
This trial is a registry that collects information about people with hypophosphatasia to help researchers understand the condition better. It may help future studies, but it’s not a treatment trial.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of hypophosphatasia (HPP).
- Your lab test shows low alkaline phosphatase (ALP) for your age/sex, OR you have a known ALPL gene mutation.
- You (or your parent/legal representative) can read and understand the study materials and questionnaires in your local language.
- You and your doctor can sign consent forms, and you agree to share your medical records for the study.
- You are not currently enrolled in an Alexion-sponsored clinical trial (this registry won’t stop you from joining future trials).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new medicine called ALE1 for hypophosphatasia (HPP), a rare bone condition. It first checks safety in healthy volunteers, then tests if the medicine helps people with HPP.
This study follows people who already have hypophosphatasia (HPP) to better understand how the condition changes over time. It may help doctors recognize patterns and improve care, even if you are not receiving a new treatment.
This study follows children with hypophosphatasia (HPP) to better understand how they do while receiving asfotase alfa. It may help improve care for families living with pediatric-onset HPP.
This study looks at how changes in the ALPL gene affect the natural course of hypophosphatasia (HPP). It aims to learn more about the condition in people who have not received enzyme replacement therapy.
This study aims to find better ways to diagnose hypophosphatasia (HPP) in adults who see a rheumatologist. If your doctor suspects HPP and you have a low ALP blood test, you may be able to help researchers develop a screening tool.
This is a long-term observational study (not a drug trial) that follows adults with signs of hypophosphatasia, a condition linked to very low alkaline phosphatase levels and sometimes a gene change. It aims to better understand the condition over time and how symptoms look and progress.
Hear when a new Hypophosphatasia (HPP) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.