Clin2
NCT02468024Possibly a fitRecruiting

Surgery or focused radiation for early lung cancer

Non-Small Cell Lung Cancer

Part of Cancer, Lungs & breathing clinical trials.

This study compares two treatments—removing only part of the lung (sublobar resection) versus a focused radiation approach (stereotactic ablative radiotherapy)—for early-stage non-small cell lung cancer. It aims to see which option works better with fewer problems for the right patients.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
272 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • Your lung cancer must be biopsy-proven non-small cell lung cancer within the last 180 days.
  • Your tumor must be 4 cm or smaller and in a peripheral (outer) part of the lung.
  • There must be no spread to distant organs, and lymph nodes in the chest must test negative after biopsy within 180 days.
  • You must have breathing test results (PFTs) within 180 days, or a thoracic surgeon must confirm you’re still eligible even if you can’t do the tests.
  • You need to be an “at high risk for major surgery” patient (based on lung function/heart-lung measurements or a surgeon’s documented judgment).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07780591Not yet recruiting
Comparing two types of lung surgery for early-stage lung cancer

This study compares two types of lung surgery for early-stage lung cancer: removing only the tumor part (segmentectomy) versus removing a larger portion (lobectomy). The goal is to see if the less invasive surgery works just as well while preserving more healthy lung tissue.

NCT07698990Not yet recruiting
Comparing two lung surgeries for early-stage lung cancer

This study compares two types of lung cancer surgery for early-stage tumors: removing only the part of the lung with the tumor (segmentectomy) versus removing the entire lobe (lobectomy). It aims to see if the smaller surgery works just as well and might be easier to recover from.

Shanghai, Shanghai Municipality
NCT04933903Recruiting· Phase 2
Neoadjuvant low-dose radiation plus immunotherapy before lung surgery

This trial tests whether giving low-dose focused radiation and two immunotherapy drugs before lung surgery can improve outcomes for people with operable, resectable non-small cell lung cancer. It aims to shrink or control the cancer before surgery and help reduce the chance it comes back.

Providence, Rhode Island
NCT01803542Recruiting· Phase 2
Stereotactic radiation for lung metastases or early lung tumors

This trial studies a precise, high-dose radiation technique (SBRT) to treat tumors in the lungs. It may help control cancer in people who either have early-stage lung cancer that is not fully operable or have limited lung metastases from other cancers.

Toronto, Ontario
NCT06646770Not yet recruiting
Segment removal versus lobe removal for small lung cancer

This study compares two types of lung surgery for people with early-stage non-small cell lung cancer (a common type of lung cancer). One surgery removes a small part of the lung (segment), the other removes an entire lobe (a larger section of the lung). The goal is to see which approach offers better outcomes for tumors that are between 2 and 3 centimeters across and are solid (not just ground-glass).

Istanbul
NCT06718309Recruiting· Phase 2
Chemo and immunotherapy with targeted radiation before surgery for lung cancer

This trial tests giving chemotherapy, immunotherapy, and targeted radiation before surgery for people with non-small cell lung cancer that can be removed. The goal is to see if this combination shrinks tumors and improves outcomes.

Hangzhou, Zhejiang

Hear when a new Non Small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.