Nerve block for severe cancer bone pain
Part of Pain clinical trials.
This study tests an experimental drug, resiniferatoxin, given as an injection near the nerves to treat severe bone pain caused by cancer that hasn't been relieved by standard treatments. The goal is to see if it can reduce pain and improve quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have cancer that has spread to the bone, causing moderate to severe pain in your chest or lower body that hasn't been helped by usual treatments like strong painkillers.
- You are not currently seeking or receiving treatments meant to cure your cancer (like chemotherapy or immunotherapy). Palliative treatments to relieve symptoms are okay.
- Your average worst pain score is 6 or higher on a 0–10 scale, and you've had a test injection that temporarily reduced your pain by at least 30%.
- You must be able to stop taking blood-thinning medications (like aspirin or Coumadin) at least 7 days before the procedure, and be willing to follow certain safety rules.
- You must have a responsible adult to help you with daily activities through the 14-day follow-up visit, and be willing to assign a Durable Power of Attorney for research and medical care.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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