Immune cell therapy for advanced melanoma
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests a treatment that uses your own immune cells, called tumor-infiltrating lymphocytes (TILs), to fight melanoma. Some participants also get a drug called pembrolizumab. The goal is to see if this approach can shrink tumors.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have metastatic melanoma that can be measured and has at least one tumor that can be removed for this treatment.
- You have already had at least one previous treatment for metastatic melanoma.
- You are between 18 and 72 years old.
- You are generally in good health, able to care for yourself, and have adequate organ function.
- If you have brain metastases, they must be small, few, and not causing symptoms, or have been treated and stable.
- You must be willing to use effective birth control and follow specific safety rules.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new treatment called ADP-TILIL7 for people with advanced melanoma. It uses your own immune cells (T-cells) that are taken from a tumor, multiplied in a lab, and then given back to you to fight the cancer. The goal is to see if this treatment is safe and works better than standard options.
This trial tests a personalized cell therapy using your own immune cells (TILs) grown in a lab. It is for people with advanced melanoma that did not respond to or stopped responding to prior immunotherapy.
This trial tests a new way to treat advanced melanoma by taking immune cells from your tumor, enhancing them in the lab to fight better, and giving them back to you. It is for people whose melanoma has spread or cannot be removed, and who have already tried standard treatments.
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This trial tests a new T-cell therapy made from your own tumor (TILs), genetically edited to remove the PD1 checkpoint blocker. It may help your immune system fight melanoma that has not responded to standard treatments like anti-PD1 therapy.
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