PET scan guided cell therapy for advanced melanoma
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests whether a special PET scan can help guide treatment with lifileucel (a cell therapy made from your own tumor) for advanced melanoma that has not responded to other treatments. The goal is to see if the scan can predict how well the cell therapy works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have stage IV melanoma or advanced stage III melanoma that cannot be removed with surgery.
- Your cancer has gotten worse after at least one prior treatment including a PD-1 blocker, and if you have a BRAF mutation, also after a BRAF or BRAF/MEK inhibitor.
- You have at least two tumors that can be removed with minor surgery (hospital stay expected to be 3 days or less) to make the cell therapy, and at least one other measurable tumor to watch.
- You are healthy enough for daily activities (ECOG score of 0 or 1) and are at least 18 years old.
- You can have treatment with lifileucel (AMTAGVI) as recommended by your doctor.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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