Clin2
NCT02978677Possibly a fitNot yet recruiting

Proton therapy dose escalation for atypical or anaplastic meningioma

Meningioma

Part of Brain & nervous system, Cancer clinical trials.

This trial tests whether a higher dose of proton therapy, a precise type of radiation, can better control a rare and more aggressive form of meningioma brain tumor. It aims to improve outcomes for patients who have had surgery and need radiation.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
90 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with an atypical (grade II) or anaplastic (grade III) meningioma and are recommended for radiation therapy.
  • You have had an MRI and a PET scan to evaluate any remaining tumor after surgery.
  • You are in generally good health, able to care for yourself (Karnofsky score of at least 60, ECOG 2 or less).
  • You have not had radiation to the brain before.
  • You do not have the tumor in multiple brain regions or spread to the spine.
  • You do not have other active cancers or are pregnant, and you can undergo MRI scans.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06830356Recruiting
PET-guided radiation for high-risk meningiomas

This trial uses a special PET scan to find active tumor areas and then delivers a stronger dose of radiation to those spots. It is for people with aggressive or returning meningiomas who have not had brain radiation before.

Aviano, Pordenone
NCT06036706Recruiting
Radiation types and thinking skills for skull base meningioma

This study compares different radiation methods for treating a slow-growing, non-cancerous brain tumor at the base of the skull. It aims to see which approach best protects memory and thinking abilities.

Caen
NCT06557512Recruiting
Focused radiation after surgery for certain meningiomas

This study tests a type of focused radiation therapy (called stereotactic radiosurgery) given after surgery for certain meningiomas. The goal is to see if this treatment helps prevent the tumor from coming back, and to check its safety.

San Francisco, California
NCT04278118Recruiting
Proton radiation study for non-cancer brain tumor types

This trial tests a radiation plan that gives treatment in fewer, larger “fractions” using proton beams (or sometimes photon beams) for certain non-cancer brain tumor types. It aims to see how well this approach works while keeping side effects manageable.

Atlanta, Georgia
NCT04127760Not yet recruiting
Radiation after surgery for atypical meningioma

This study tests whether giving radiation therapy after surgery helps prevent atypical meningioma from coming back. It is for people who had the tumor completely removed and are between 18 and 70 years old.

NCT05768087Recruiting
Testing higher-dose proton radiation for new glioblastoma

This trial is testing an escalated dose of proton beam radiation, along with standard chemotherapy and MRI-guided planning, for newly diagnosed glioblastoma. It aims to see whether the higher radiation dose can improve treatment while staying safe for nearby critical brain structures.

Aarhus, Central Jutland

Hear when a new Meningioma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.