Genetic testing study for inherited AML or MDS risk
Part of Blood & lymphatic, Cancer clinical trials.
This study uses advanced DNA testing to look for inherited gene changes in people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). It may help explain whether your illness could be part of a family-linked risk syndrome, which can guide treatment and family planning.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS)
- A close family member (parent, sibling, child, or grandparent) has AML or MDS, or another myeloid blood cancer
- OR a close family member has a lymphoma or other lymph “blood cancer”
- OR you have personal signs that can fit certain inherited MDS/AML risk patterns (examples like easy bruising/low platelets, unusual nail/skin/oral changes, lung scarring with no clear cause, liver problems with no clear cause, swollen limbs, unusual infections, or immune problems)
- You are able and willing to sign informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study collects and stores blood and bone marrow samples from young people with certain blood cancers so doctors can do genetic (“genomic”) testing now and in the future. It may help improve understanding of the disease and support better matching of care for patients.
This study collects family and medical history to better understand inherited causes of blood cancers (like lymphoma) and related conditions. It may help researchers build genetic findings that could improve how families understand their risk and future care.
This study looks at gene patterns in people with blood cancers to better understand the disease and find possible treatments. If you are being tested for a blood cancer or have a blood cancer that came back or got worse, you may be able to join.
This study uses advanced tests (genetics and other 'omics' methods) to better understand your leukemia and find a treatment that targets its specific features. It may help if standard treatments haven't worked or stopped working.
This trial studies whether certain inherited genes increase the risk of myeloid cancers or bone marrow failure. You will provide a DNA sample via a skin biopsy to look for these genetic changes.
This trial looks at how childhood, teen, and young adult acute myeloid leukemia (AML) changes at the genetic level and how cells respond to multiple drugs. It may help doctors understand which treatments work best and how leukemia interacts with supportive cells in the bone marrow.
Hear when a new Leukemia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.