Preserving tissue in near-complete rectal cancer response
Part of Cancer, Digestive system clinical trials.
This trial studies whether it’s safe to preserve the rectum (instead of removing it right away) for people with locally advanced rectal cancer who respond very well after pre-treatment radiation and/or chemotherapy. It may help some patients avoid major surgery, but eligibility depends on response seen on exam, scope, and MRI, and on having no spread to distant organs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have rectal cancer confirmed by a pathology (tissue) test called adenocarcinoma.
- You received treatment before surgery: radiation and/or chemoradiation (radiation with chemotherapy).
- About 8 weeks after that treatment, tests must show a complete or near-complete response based on exam, endoscopy (scope of the rectum), and MRI scan.
- There must be no evidence that the cancer has spread to distant organs (no distant metastases).
- You must have had the response assessed using digital rectal exam and flexible rectoscopy, plus MRI (all part of the study checks).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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