Clin2
NCT06209099Possibly a fitRecruiting

Organ preservation first for low-risk rectal cancer

Rectal Cancer

Part of Cancer, Digestive system clinical trials.

This trial tests a strategy to avoid surgery by using watchful waiting after initial treatment for early-stage rectal cancer. It may help patients keep their rectum and avoid a permanent colostomy.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
96 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You are 18 to 85 years old
  • You have a new diagnosis of rectal cancer that has not spread
  • Your tumor is small (less than 4 cm) and located near the anus
  • You have not had chemotherapy, radiation, or surgery for rectal cancer before
  • You are in good general health (ECOG score 0-1)
  • Your blood counts and liver/kidney function are within normal limits

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06740357Recruiting
Shared decision-making for rectal cancer organ preservation

This trial tests a program that helps you and your doctor decide together whether to avoid surgery and keep your rectum after chemo and radiation. It's for people with early-stage rectal cancer who have not had prior treatment for this cancer.

Dijon
NCT07070622Recruiting· Phase 3
Organ preservation for low rectal cancer after chemo

This trial tests whether chemotherapy alone can help avoid surgery for low rectal cancer. It is for people with tumors close to the anus that haven't spread far, and who haven't had prior cancer treatment.

Chengdu, Sichuan
NCT06249672Recruiting
Long-term outcomes after rectal preservation for rectal cancer

This study looks at how well people with rectal cancer do over time when they try to keep their rectum instead of having surgery. It is for patients who have already had chemoradiation and whose tumor has shrunk to a small scar (2 cm or less).

Bern
NCT05772923Recruiting
Testing rectal cancer organ-preservation after radiation

This trial compares two ways to preserve the rectum/avoid major surgery after radiation: a focused contact x-ray treatment versus waiting longer and then removing only a small area if needed. It may help some people keep more normal bowel function while still controlling the cancer.

Nijmegen, Gelderland
NCT06599827Not yet recruiting· Phase 2
Pre-surgery treatment for high-risk rectal cancer

This study tests a new combination of treatment before surgery for high-risk rectal cancer. It combines a shorter course of radiation with chemotherapy and immunotherapy (which helps your immune system fight cancer) to see if it shrinks the tumor and improves outcomes.

Shanghai, Shanghai Municipality
NCT05927584Recruiting
Local removal for early rectal cancer without extra treatment

This trial studies removing an early rectal cancer tumor locally (through the rectum/anal area) with no additional therapy afterward. The goal is to preserve organs and maintain quality of life while still trying to cure the cancer.

Madrid

Hear when a new Rectal Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.