Weekly paclitaxel before surgery, using tumor tests to guide care
Treatments studied
Part of Cancer, Women’s health & pregnancy clinical trials.
This trial gives weekly paclitaxel chemotherapy before breast surgery, then studies tumor “biomarkers” to see how well treatment is working. The goal is to improve how doctors predict which patients benefit and who may need different approaches.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed breast cancer that is being treated with chemotherapy before surgery (called “neoadjuvant”).
- Your cancer has not spread to other organs (no metastatic disease) based on staging tests.
- You can take weekly paclitaxel, and you will not receive other cancer medicines during the paclitaxel treatment.
- You must have enough saved tumor tissue from a prior biopsy (at least 8 slides), and it should be from the breast tumor or a lymph node.
- You must be able to get repeat imaging after 4 treatment cycles and before surgery to measure tumor response.
- You must be willing to have another biopsy of the breast tumor or lymph node during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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