Personalized chemo before breast cancer surgery
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests whether giving chemotherapy before surgery, guided by the genetic profile of your tumor, can improve outcomes for a specific type of HER2-positive breast cancer. It aims to tailor treatment to each person's cancer biology.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must have HER2-positive breast cancer that hasn't spread beyond the breast or nearby lymph nodes (stages T1c to T3 and N0 to N2).
- Your tumor must show a HER2-enriched pattern on a special gene test (MammaPrint/BluePrint).
- You cannot have received any treatment yet for this breast cancer.
- Your heart function (left ventricle pumping strength) must be at least 50%.
- Your organs (kidneys, liver, bone marrow) must work well enough, as shown by blood tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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