Olanzapine to prevent nausea during chemo in children
Treatments studied
Part of Cancer clinical trials.
This study tests whether adding olanzapine can better control nausea (CIV) in children getting very nausea-causing chemotherapy or transplant treatment. It may help reduce severe nausea and vomiting while they’re in the hospital.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are planning to start “highly emetogenic” chemotherapy or a stem cell transplant conditioning treatment soon
- You can stay in the hospital from the first study drug dose until 24 hours after the last dose
- Your child is between 2.5 and under 18 years old and weighs at least 12.5 kg
- Recent blood and heart tests (within the week before chemo/transplant conditioning) are within allowed ranges
- The child will receive continuous anti-nausea medicine (like ondansetron, granisetron, or palonosetron) during treatment
- If the patient could become pregnant, they have a negative pregnancy test and agree to reliable birth control
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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