Treatment
Olanzapine clinical trials
We’re tracking 32 recruiting studies that include Olanzapine, each written for real people, not researchers, below.
Recruiting studies
- NCT06338683RecruitingPhase 3
Olanzapine for advanced upper digestive and lung cancer survival
This study tests whether a medicine called olanzapine can improve survival in people with advanced cancers of the upper digestive system or lungs. Olanzapine may help with appetite and weight, which are common problems in these cancers.
Xining, QinghaiAges 18–80 - NCT06517199RecruitingPhase 3
Olanzapine for cancer-related appetite and weight loss
This trial tests whether the drug olanzapine can help improve appetite and reduce weight loss in people with advanced cancer who are not currently receiving chemotherapy or other anti-cancer treatment. It may be an option if you have lost weight and have little appetite.
BangkokAges 18 years+ - NCT07743827Recruiting
Olanzapine-based steroid-sparing anti-nausea treatment for breast cancer
This trial tests a new anti-nausea medicine combination for breast cancer patients getting AC chemotherapy, specifically designed for those with diabetes, obesity, or other metabolic issues. It aims to reduce the need for steroids, which can be riskier for these patients.
Alexandria, Alexandria GovernorateAges 18–70 - NCT06850454RecruitingPhase 3
Olanzapine vs placebo for nausea from first chemo
This study tests if the drug olanzapine (commonly used for nausea) can help prevent vomiting in people receiving moderately strong chemotherapy for the first time. It may be a good fit if you're about to start treatment with oxaliplatin, irinotecan, or carboplatin and haven't had severe nausea treatments before.
Bangkok, BangkokAges 18 years+ - NCT07208305RecruitingPhase 3
Testing a drug combo for opioid-related nausea
This study tests whether the combination of olanzapine and metoclopramide can prevent nausea and vomiting caused by strong painkillers (opioids) in people with advanced cancer. If you are starting a strong opioid for pain and have not had nausea or vomiting recently, this study may be for you.
Xining, QinghaiAges 18 years+ - NCT05669742RecruitingPhase 3
Empagliflozin plus olanzapine to reduce metabolic side effects
This trial tests whether adding empagliflozin to standard olanzapine treatment can improve metabolic problems (like blood sugar and cholesterol changes) that can happen with olanzapine in people with schizophrenia. If you qualify, you would be closely monitored for benefits and side effects.
TantaAges 18–65 - NCT05170919Enrolling by invitationPhase 2
Olanzapine vs mirtazapine for weight loss in advanced cancer
This Phase 2 study tests whether the medicines olanzapine or mirtazapine can help people with advanced cancer who are losing weight without trying. It looks at improving unintentional weight loss when standard cancer care is also ongoing.
Englewood, New JerseyAges 18 years+ - NCT05705492RecruitingPhase 2
Olanzapine to help cancer-related weight and appetite loss
This Phase 2 trial tests whether olanzapine can help people with advanced cancer who are losing weight and not eating enough. It looks for improvements in appetite and weight while you receive your first-line palliative cancer treatment.
Portland, OregonAges 18 years+ - NCT07699276RecruitingPhase 2
Steroid-sparing nausea drug combo for high-dose chemo
This trial tests if combining two anti-nausea drugs (olanzapine and palonosetron) can prevent vomiting and nausea without using steroids in people receiving high-dose cisplatin chemotherapy for their first time.
BangkokAges 18 years+ - NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+ - NCT06200181RecruitingPhase 3
Olanzapine for opioid misuse in cancer pain
This study tests if a medication called olanzapine can help reduce cravings and misuse of opioid pain medicines in people with cancer pain. You would take olanzapine or a placebo daily for a few weeks while continuing your usual care.
Houston, TexasAges 18 years+ - NCT06554613RecruitingPhase 2
Olanzapine with first-line immunotherapy for advanced lung cancer trial
This trial tests whether adding the drug olanzapine to standard first-line immunotherapy (with or without chemotherapy) can help people with advanced lung cancer that does not have an EGFR mutation. It aims to improve treatment outcomes and quality of life.
Nanchang, JiangxiAges 18–75 - NCT06588413RecruitingPhase 3
Comparing two doses of olanzapine for nausea after stem cell transplant
This trial tests whether a lower dose of olanzapine (2.5 mg) works as well as the usual dose (5 mg) for preventing nausea and vomiting caused by high-dose melphalan chemotherapy. It is for people receiving their own stem cell transplant.
Augusta, GeorgiaAges 18 years+ - NCT06740890RecruitingPhase 4
Exercise and a new medication for schizophrenia or bipolar disorder
This study tests whether a combination of a daily medication (olanzapine-samidorphan) and a structured exercise program can help people with schizophrenia, schizoaffective disorder, or bipolar disorder improve their health and well-being.
New York, New YorkAges 18–65 - NCT06995508RecruitingPhase 2
Olanzapine for appetite loss in head and neck cancer patients
This trial tests if the drug olanzapine can help improve appetite in people with head and neck cancer who are getting chemotherapy and radiation. It aims to prevent or reduce weight loss during treatment.
Buffalo, New YorkAges 18 years+ - NCT07246187RecruitingPhase 3
Comparing two drugs for cannabis-related nausea in the ER
This trial tests whether haloperidol or olanzapine works better to stop severe nausea and vomiting caused by heavy cannabis use. If you use cannabis nearly daily and have had episodes of vomiting that come and go, this study may help find the best treatment for you.
Toledo, OhioAges 18–100 - NCT07263191Recruiting
Olanzapine study for bipolar disorder
This study looks at how well patients with bipolar disorder do while taking the medication olanzapine. You will continue your regular treatment, and answer questions about your experience.
SeongnamAges 19 years+ - NCT07413809RecruitingPhase 3
Preventing nausea after stem cell transplant: olanzapine vs dexamethasone
This trial compares two anti-nausea drug regimens (one with olanzapine, one with dexamethasone) to prevent delayed nausea and vomiting after a stem cell transplant for multiple myeloma. It aims to find which is better at controlling these side effects.
Ningbo, ZhejiangAges 18–65 - NCT07633236RecruitingPhase 3
Olanzapine to prevent appetite and weight loss during cancer chemotherapy
This study tests whether olanzapine, a medication that can increase appetite, helps prevent severe appetite loss and muscle wasting in patients with ovarian or stomach cancer who are receiving chemotherapy before surgery. The goal is to help patients maintain nutrition and strength during treatment.
MoscowAges Any age - NCT07565428RecruitingPhase 3
Study of roluperidone for negative symptoms of schizophrenia
This trial tests a new medicine called roluperidone for people with schizophrenia who have ongoing negative symptoms (like low motivation or social withdrawal) but stable positive symptoms (like hallucinations). It aims to see if the drug helps with these symptoms and if it can reduce the chance of relapse compared to other medications.
Bellflower, CaliforniaAges 18–55 - NCT07482891RecruitingPhase 4
Preventing nausea and vomiting from multi-day chemo
This study tests if two medicines given together, fosaprepitant and palonosetron, can prevent nausea and vomiting caused by strong chemotherapy given over several days. It's for people who have never had chemo before and are about to start a multi-day treatment for a solid tumor.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05814640RecruitingPhase 1/Phase 2
STAR-AD: Testing stepwise treatment for teen depression
This trial tests a step-by-step approach to treating moderate-to-severe depression in teens. It may help find a treatment path that improves mood while keeping care safe, including for some teens who have suicidal thoughts but do not need inpatient care.
Chongqing, ProvinceAges 13–18 - NCT04478838RecruitingPhase 4
Alternate-day antipsychotic dosing for schizophrenia
This trial looks at whether taking an antipsychotic every other day can keep symptoms controlled in adults with schizophrenia or another psychotic disorder. It may help some people avoid daily dosing, but it requires specific medication stability and screening checks.
Toronto, OntarioAges 18 years+ - NCT05303064RecruitingPhase 3
Study of weight gain medicine for teens with certain mood or psychosis
This Phase 3 study tests a treatment aimed at reducing unhealthy weight gain in teens with schizophrenia or bipolar I disorder, using changes in BMI (a height-and-weight measure). It may help families who are concerned about weight changes that can happen with some psychiatric medicines.
Dothan, AlabamaAges 10–17
What Olanzapine is being studied for
Conditions with recruiting Olanzapine studies.
Common questions
- Are there clinical trials studying Olanzapine?
- Yes. Clin2 currently lists 32 recruiting studies that include Olanzapine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Olanzapine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Olanzapine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Olanzapine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.