Testing a drug combo for opioid-related nausea
Treatments studied
Part of Digestive system clinical trials.
This study tests whether the combination of olanzapine and metoclopramide can prevent nausea and vomiting caused by strong painkillers (opioids) in people with advanced cancer. If you are starting a strong opioid for pain and have not had nausea or vomiting recently, this study may be for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have advanced cancer that is causing moderate to severe pain (a score of 4 or more out of 10 on a pain scale).
- You must be starting a strong opioid painkiller (like morphine or oxycodone) for the first time.
- You must be at least 18 years old and able to swallow pills.
- You should not have had nausea, vomiting, or an intestinal blockage recently.
- You must not have had chemotherapy or radiation in the last month.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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