Tested special immune-targeting treatment after abdominal infection surgery
Part of Digestive system, Infections clinical trials.
This Phase 2 study tests whether Pentaglobin®, a blood-product made from immune proteins, helps critically ill people with severe abdominal infection (peritonitis) after the infection source is surgically cleaned up. It targets patients with signs of strong inflammation and severe illness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of secondary or quaternary peritonitis (an abdominal infection related to another problem).
- The surgery or minimally invasive procedure to control the infection must happen within 6 hours of when it was scheduled in the study.
- You must be very sick from infection (sepsis and/or septic shock) and have a SOFA score of 8 or higher.
- Your blood test shows IL-6 at least 1000 pg/mL (a marker of inflammation).
- Antibiotics must start within 12 hours of being admitted to the ICU.
- You (or your legal representative) must sign informed consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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