Study of genetics and causes of systemic juvenile arthritis and Still's disease
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This study aims to learn more about the causes and genetics of two related inflammatory conditions: systemic juvenile idiopathic arthritis (sJIA) in children and adult-onset Still's disease (AOSD) in adults. By studying patients and healthy volunteers, researchers hope to understand these diseases better and find better ways to treat them.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with systemic juvenile idiopathic arthritis (sJIA) or adult-onset Still's disease (AOSD), or you are a healthy family member or volunteer.
- For children under 16, a diagnosis of sJIA must meet standard criteria. For teens and adults (16+), the diagnosis must meet the Yamaguchi criteria (and for AOSD, negative ANA and RF tests).
- If you are pregnant and have Still's disease, you can join, but you won't need to have a skin biopsy or bone marrow test.
- Healthy volunteers must be 2 years or older and have no history of autoimmune, inflammatory, or cancer conditions.
- You must be able to provide consent (or have a parent/guardian for minors) and attend follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study follows people with spondyloarthritis (an inflammatory arthritis that often affects the spine and joints) and their family members over time to better understand how the disease develops and progresses. It also includes a research stool sample test to learn about gut bacteria.
This is a long-term study that collects health information and lab samples from people who have certain diagnoses of recurring (coming and going) inflammatory fevers and related joint or immune conditions. It may help researchers better understand these diseases and how they work over time.
This study collects health information from people with adult-onset Still's disease and similar autoinflammatory conditions to better understand these diseases. By joining, you contribute to research that may lead to better care in the future.
This study follows children and young adults newly diagnosed with certain types of arthritis or related conditions to learn more about their health over time. It may help doctors better understand how these diseases progress and how treatments work.
This study follows children and teens who have an inflammatory rheumatism condition that started in childhood. It aims to better understand these illnesses and how they affect young people over time.
This study creates a personalized medicine network to better understand and treat childhood arthritis. If you have JIA or unexplained joint inflammation, researchers will look at your biology to find the best treatment approach for you.
Hear when a new Still's Disease, Adult-Onset trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.