Gentamicin treatment for certain skin blistering disease
Part of Genetic & congenital, Skin clinical trials.
This trial tests gentamicin, an antibiotic, for junctional epidermolysis bullosa (JEB) caused by a specific kind of genetic change in the LAMB3 gene. It may help some people with this exact mutation, but you must meet several safety and genetic requirements to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have junctional epidermolysis bullosa (JEB).
- Your genetic test shows a “nonsense” mutation in the LAMB3 gene (in one or both copies).
- You do not already have hearing problems.
- You do not already have kidney problems.
- You are not allergic to gentamicin (an aminoglycoside) or to sulfate-containing medicines.
- You are not pregnant. (If applicable, you must follow the study’s pregnancy rules.)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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