Tracking outcomes of fecal transplant for repeated C. difficile
Treatments studied
Part of Infections clinical trials.
This study looks at how fecal microbiota transplantation (a transplant of healthy gut bacteria) works for people who get C. difficile infection repeatedly. It also focuses on collecting follow-up information to better understand which patients benefit and how.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had C. difficile come back at least two times, with confirmed positive tests and symptoms that returned within about 2 to 8 weeks after the last positive test.
- You tried standard antibiotic treatment with metronidazole and/or vancomycin by mouth, but it did not work for you.
- You have had a severe episode that sent you to the hospital and did not improve with standard antibiotic treatment.
- You must be at least 16 years old.
- You should not have severe stomach/colon swelling that puts you at risk of a colon tear (perforation).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies using a fecal microbiota transplant (FMT)—healthy gut bacteria moved from a screened donor—to help treat recurring or hard-to-control C. difficile infection. It may help restore a healthier gut environment when standard treatments keep failing or the infection returns.
This study looks at how well fecal microbiota transplantation (FMT) works over time and checks its safety. If you have received at least one FMT for a qualifying condition, you may be able to participate.
This trial studies whether fecal microbiota transplantation (a procedure that transfers healthy stool bacteria) can change a person’s gut bacteria after repeated C. difficile infection. It may help reduce recurring infections by restoring a healthier balance of gut microbes.
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
This trial tests if capsules containing fecal microbiota can prevent further Clostridioides difficile infections in people who have had at least two recurrences. If you've had multiple C. diff infections and your symptoms go away with antibiotics, this treatment might help keep them from coming back.
This Phase 2 study tests whether placing stool from a healthy donor into your gut can treat repeated, hard-to-control C. difficile colitis. It may help restore healthy gut bacteria and reduce future flare-ups.
Hear when a new Clostridium Difficile Infection Recurrence trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.