Fecal microbiome transplant for repeat C. difficile infection
Treatments studied
Part of Digestive system clinical trials.
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be age 3 to 21 (inclusive)
- You have inflammatory bowel disease diagnosed by standard tests, or you have moderate-to-severe or repeat C. difficile infection
- You (or your guardian) can complete the study interviews and physical exam
- You must be able to give informed consent (and assent if needed for your age)
- On the transplant day, anyone who could become pregnant may need a urine pregnancy test
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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Other trials that look related to this one.
This trial tests whether one or multiple fecal transplants from a healthy donor can help treat both a recurring C. diff infection and active ulcerative colitis. It aims to find the best schedule for the procedure.
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
This trial studies using a fecal microbiota transplant (FMT)—healthy gut bacteria moved from a screened donor—to help treat recurring or hard-to-control C. difficile infection. It may help restore a healthier gut environment when standard treatments keep failing or the infection returns.
This Phase 1 study tests a stool-based treatment approach for people who keep getting C. difficile diarrhea that returns after antibiotics. The goal is to see whether the treatment is safe and works to stop future episodes.
This Phase 2 study tests whether placing stool from a healthy donor into your gut can treat repeated, hard-to-control C. difficile colitis. It may help restore healthy gut bacteria and reduce future flare-ups.
This trial studies whether fecal microbiota transplantation (a procedure that transfers healthy stool bacteria) can change a person’s gut bacteria after repeated C. difficile infection. It may help reduce recurring infections by restoring a healthier balance of gut microbes.
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