Fecal transplant to change gut bacteria in C. difficile infection
Part of Infections clinical trials.
This trial studies whether fecal microbiota transplantation (a procedure that transfers healthy stool bacteria) can change a person’s gut bacteria after repeated C. difficile infection. It may help reduce recurring infections by restoring a healthier balance of gut microbes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have repeated (recurrent) C. difficile gut infection
- You are between 18 and 90 years old
- You can understand the study and sign a consent form
- You can follow the study schedule for check-ups and procedures
- You do not have another active stomach or intestinal infection besides C. difficile
- You have not had recent medicines or products that can change gut bacteria (like antibiotics or probiotics in the last 6 weeks)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests if capsules containing fecal microbiota can prevent further Clostridioides difficile infections in people who have had at least two recurrences. If you've had multiple C. diff infections and your symptoms go away with antibiotics, this treatment might help keep them from coming back.
This trial studies using a fecal microbiota transplant (FMT)—healthy gut bacteria moved from a screened donor—to help treat recurring or hard-to-control C. difficile infection. It may help restore a healthier gut environment when standard treatments keep failing or the infection returns.
This trial tests whether one or multiple fecal transplants from a healthy donor can help treat both a recurring C. diff infection and active ulcerative colitis. It aims to find the best schedule for the procedure.
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
This Phase 2 study tests whether placing stool from a healthy donor into your gut can treat repeated, hard-to-control C. difficile colitis. It may help restore healthy gut bacteria and reduce future flare-ups.
This trial tests whether giving a stool transplant (also called FMT) can treat a new, early C. difficile infection in people who have improved while on antibiotics. It may help some people prevent the infection from coming back or worsening.
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