Clin2
NCT03646955Possibly a fitRecruiting

Partial breast radiation versus no radiation after lumpectomy

Local Neoplasm RecurrenceDistantly Metastatic Malignant NeoplasmDeathFibrosis BreastDepigmentation/Hyperpigmentation of SkinTelangiectasiaScarPain

Part of Cancer, Heart & circulation, Pain, Skin clinical trials.

This trial compares giving radiation only to part of the breast versus not giving radiation at all after breast-conserving surgery. It’s meant for women with early, hormone-driven breast cancer to see if skipping radiation can be safe and reduce treatment burden.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
926 people
Ages
60 years and older
Study type
Interventional

Who can take part

  • You are a woman age 60 or older
  • Your cancer is in one breast area only (unifocal) and is grade 1 or 2
  • Your lymph nodes are negative based on a sentinel node or lymph node removal
  • Your tumor is estrogen-receptor positive (ER at least 10%) and HER2 is negative
  • Your breast surgery was a lumpectomy (breast conservation), with clear margins (at least 2 mm)
  • No signs of spread to distant organs, and you have enough health to do follow-up (ECOG 0–2)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04669873Recruiting
Partial breast radiation vs whole breast radiation after lumpectomy

This trial studies whether treating only part of the breast with radiation works as well as treating the whole breast in people with early breast cancer after lumpectomy. It may help reduce radiation exposure to healthy tissue, while still controlling the cancer.

São Paulo, São Paulo
NCT07654257Not yet recruiting· Phase 2
Single radiation treatment after lumpectomy for early breast cancer

This trial tests a single, targeted radiation treatment given during or after lumpectomy for early-stage breast cancer. It aims to make treatment more convenient while keeping the same safety and effectiveness as longer radiation courses.

Richmond, Virginia
NCT07757958Not yet recruiting· Phase 3
Partial breast radiation without lymph node biopsy for early breast cancer

This trial tests whether radiation to only part of the breast is safe and effective for women with early-stage breast cancer, without removing lymph nodes. The goal is to reduce side effects while keeping the cancer from coming back.

Seoul
NCT05417516Recruiting· Phase 3
Partial breast radiation after lumpectomy in early breast cancer

This trial compares a shorter course of radiation focused on part of the breast versus a standard approach after lumpectomy. It aims to see if treating a smaller area can control the cancer while reducing treatment burden.

Darlinghurst, New South Wales
NCT06362616Recruiting
Pre-surgery partial breast radiation for recurrent breast cancer

This trial tests a shorter course of radiation to just part of the breast before surgery for women who have had breast cancer return in the same breast. It's for those who have already had radiation to that breast and have a specific type of cancer (ER+, HER2-).

Amsterdam
NCT06615466Recruiting
Short radiation course for early stage breast cancer

This trial tests a shorter, more intense radiation schedule for women with early stage breast cancer after lumpectomy. It aims to provide effective treatment with fewer visits, which may be more convenient for patients.

Beijing, Beijing Municipality

Hear when a new Death trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.