Proton radiation plus two chemo drugs for unresectable pancreatic cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests how safe and effective nab-paclitaxel plus gemcitabine chemo is when paired with proton radiation for locally advanced pancreatic cancer that cannot be removed with surgery. It may help shrink the tumor and improve local control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your pancreatic cancer must be proven by biopsy (adenocarcinoma) under a microscope
- Your cancer must be locally advanced and not spread to distant sites (no liver/lung/peritoneal spread)
- Surgery must not be possible because the tumor blocks or presses major nearby blood vessels
- You must be well enough to function day to day (ECOG 0–1) and have adequate blood counts (neutrophils and platelets)
- Your kidney and liver tests must be within limits (creatinine clearance >45, bilirubin ≤2)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a home-wearable tumor-treating device (Tumor Treating Fields) combined with gemcitabine and albumin-bound paclitaxel works better as first treatment for locally advanced pancreatic cancer. It may help by targeting cancer cells while also using standard chemotherapy.
This trial compares two different chemotherapy combinations, each paired with immunotherapy and radiation, as the first treatment for locally advanced pancreatic cancer. It aims to see which combination works better.
This trial studies NovoTTF-200T(P), a portable treatment device, combined with standard chemotherapy (gemcitabine and nab-paclitaxel) for people with resectable pancreatic adenocarcinoma. It aims to improve treatment results by trying this combination before surgery.
This trial tests whether giving proton radiation and chemotherapy before surgery can shrink or control “borderline resectable” pancreatic cancer so it can be removed more effectively. It may help by improving treatment response while planning for surgery afterward.
This trial studies a chemotherapy combination (albumin-bound paclitaxel and gemcitabine) as first treatment for pancreatic cancer that cannot be removed by surgery. It aims to improve outcomes by testing how well this treatment works in people with locally advanced or metastatic disease.
This trial tests whether giving two already-approved chemotherapy drugs and radiation before surgery works better for localized pancreatic cancer. It’s meant for people whose cancer looks removable by surgery and who haven’t had prior pancreatic cancer treatment.
Hear when a new Locally Advanced Pancreatic Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.