Butyrate enemas after Hirschsprung surgery
Part of Digestive system, Genetic & congenital clinical trials.
This trial tests whether giving butyrate enemas (a liquid that helps the gut lining heal) after surgery for Hirschsprung's disease can help the bowel work better sooner. It might reduce the time your baby needs to recover bowel movements after the operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby must have a confirmed diagnosis of Hirschsprung's disease in the first two months of life, and the affected part must be limited to the rectum or sigmoid colon.
- Your baby must have been born at or after 35 weeks of pregnancy.
- Your baby's bowel must have been successfully managed with daily colonic irrigations (flushing) before the corrective surgery, without needing a colostomy bag.
- Your baby must not have had a serious bowel inflammation (enterocolitis) before the trial starts.
- Your baby must not have other serious birth defects (including Down syndrome) or conditions that affect bowel function, like cystic fibrosis or thyroid problems.
- Both parents or legal guardians must give consent, and the family must be covered by French social security.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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