Clin2
NCT07343622Worth exploringNot yet recruiting

Comparing two minimally invasive surgeries for total colonic Hirschsprung disease

Total Colonic AganglionosisHirschsprung DiseaseDuhamelSoave

Part of Digestive system, Genetic & congenital clinical trials.

This trial compares two types of minimally invasive surgery to repair a rare birth defect affecting the whole large intestine (total colonic Hirschsprung disease). Your child will have already had a first surgery as a baby; this study tests which second surgery works better, using robot or laparoscopy to help with recovery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
1 month to 14 years
Study type
Interventional

Who can take part

  • Your child must have total colonic Hirschsprung disease, confirmed by a biopsy, which means the entire large intestine lacks the nerve cells needed for normal bowel function.
  • Your child must have already had a temporary colostomy or ileostomy (an opening in the belly to pass stool) shortly after birth, and will now have the main repair surgery.
  • The repair surgery will be one of these two minimally invasive methods: robot-assisted Duhamel or the modified Soave pull-through. Your child's surgeon will explain which one.
  • Your child must not have Down syndrome.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07468565Not yet recruiting
Swenson surgery for Hirschsprung disease in children

This study looks at how well the Swenson surgery works for children with Hirschsprung disease, a condition where part of the bowel is missing nerve cells. It aims to see how children do after this specific type of surgery, which might help doctors and families make decisions.

NCT05450991Recruiting
Study outcomes in children with Hirschsprung’s disease

This study looks at long-term health and development outcomes in children who were diagnosed and treated for Hirschsprung’s disease or anorectal malformations. It uses both numbers and interviews to understand what happens over time after treatment, helping families and clinicians plan better care.

Liverpool, Merseyside
NCT06590142Recruiting
Studying bowel tissue for future Hirschsprung's treatments

This trial collects leftover intestine tissue from children having bowel surgery to help develop future treatments using a child's own cells. It aims to find better ways to repair the bowel without needing donor tissue.

Liverpool, Merseyside
NCT07742436Not yet recruiting
Bladder and sexual symptoms after Hirschsprung surgery

This study looks at bladder and sexual symptoms in people who had surgery for Hirschsprung disease, a condition affecting the bowel. It aims to understand long-term effects on urinary and sexual health to improve follow-up care.

Clermont-Ferrand
NCT03660176Not yet recruiting· Phase 3
Butyrate enemas after Hirschsprung surgery

This trial tests whether giving butyrate enemas (a liquid that helps the gut lining heal) after surgery for Hirschsprung's disease can help the bowel work better sooner. It might reduce the time your baby needs to recover bowel movements after the operation.

Marseille, PACA
NCT07603232Enrolling by invitation
Long-Term Health Outcomes in Children With Hirschsprung's Disease or Anorectal Malformations

This study follows children who were born with Hirschsprung's disease (a condition affecting the nerves in the colon) or anorectal malformations (differences in how the rectum or anus formed) to understand how they do over time. Researchers will track health outcomes and quality of life to help improve care for future children with these conditions.

Montreal, Quebec

Hear when a new Hirschsprung Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.