Study drugs into a tumor plus immune therapy for advanced cancer
Part of Cancer, Immune system & allergy clinical trials.
This trial tests injecting an immune-boosting mixture directly into a skin or lymph node tumor, along with immune-checkpoint medicines given through the vein. It aims to help the body recognize and fight advanced cancers that can’t be fully removed by surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You agree to the study after learning details and signing consent
- You’re 18 or older, with an advanced solid cancer that can’t be fully removed with surgery
- Your cancer has spread to the skin or lymph nodes, and there’s a target lesion that can be safely injected and biopsied
- You can likely tolerate treatment: overall activity is good (ECOG 0–1) and key blood, kidney, liver, and clotting tests meet limits
- You have a recent tumor tissue sample available for testing (archival within ~3 months or a new biopsy during screening)
- You have access for an added procedure called leucapheresis (to collect immune cells)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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