Brain scan study of an antibiotic for drug addiction
Part of Mental health clinical trials.
This study uses an MRI brain scan to see how taking clavulanic acid affects brain activity related to drug addiction. It may help researchers understand whether this medicine could change how addiction-related cues affect the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 65 years old
- Speak and read English well enough to follow instructions and tasks
- Have usable eyesight (with glasses/contacts if needed) for the study tasks
- Smoke more than 10 cigarettes per day for at least 2 years, and have a positive breath carbon monoxide test (10 ppm or higher)
- If you can become pregnant, you must have a negative urine pregnancy test
- Agree not to use any other tobacco or nicotine products (like e-cigarettes, patches, gum, or sprays) during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a beta-blocking medicine (propranolol) and nicotine patches change how strongly your brain responds to smoking cues. It may help researchers understand what drives cigarette cravings and how to reduce them.
This study tests how a medicine called cytisinicline (similar to a plant-based stop-smoking aid) affects brain activity when you see or think about smoking. It may help researchers understand how the medicine works, even if you aren't ready to quit right now.
This study looks at how a brain system called orexin may affect nicotine addiction. If you smoke regularly and meet diagnostic criteria, the trial may help researchers understand what brain changes could improve nicotine dependence.
This study tests whether a brain stimulation treatment called rTMS can help people with psychiatric conditions quit smoking. You will be randomly assigned to get either rTMS or a nicotine patch, and your progress will be tracked to see which treatment works better.
This trial tests if a type of brain stimulation (TMS) can help people with nicotine dependence reduce cravings. It may be an option if you smoke or use e-cigarettes heavily and want to understand how your brain responds to treatment.
This study uses brain imaging (MRI) and tasks to better understand what’s happening in the brain in addiction. It may help researchers improve how addiction is studied and measured using brain-based methods.
Hear when a new Tobacco Use Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.