Comparing wider versus narrower surgery margins for stage II melanoma
Part of Cancer, Skin clinical trials.
This trial studies whether removing a slightly wider strip of skin around a melanoma improves outcomes compared with a narrower strip. It also uses a lymph node staging procedure to check spread and helps doctors fine-tune surgery for stage II melanoma.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have stage II primary skin melanoma that has been fully diagnosed by biopsy, with certain depth/thickness and ulceration patterns
- Your melanoma is on the skin (not inside organs) and is in a location where a 2cm surgical margin is possible
- You can have surgery (sentinel lymph node biopsy and wide local excision) soon after diagnosis—both on the same day—with timing limits (within 120 days of diagnosis, and within 28 days of starting the study)
- You are 18 or older, can understand the study, and can follow required visits and procedures
- Your overall health is good enough (ECOG score 0–1) and your expected life span is at least 5 years
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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