Comparing less invasive surgery to standard care for older adults with early-stage melanoma
Treatments studied
Part of Cancer, Skin clinical trials.
This trial compares less invasive procedures with the current standard treatment for early-stage melanoma in adults 75 and older. The goal is to find out if these less invasive options work just as well and help patients recover better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 75 years old or older.
- You must have been newly diagnosed with early-stage melanoma and need to have surgery to remove it, including a sentinel lymph node biopsy.
- You must be well enough to have surgery, with no uncontrolled medical conditions or serious infections.
- You must be able to speak English to complete quality-of-life questionnaires.
- If you have HIV, your viral load must be undetectable while on treatment.
- You may have had other cancers if they don't interfere with this trial's safety or results.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two methods of checking removed melanoma tissue to see which gives clearer results. It may help improve how doctors determine if all cancer was removed.
This study helps doctors decide the safest surgical approach for melanoma and similar skin tumors in children and young adults by using pathology reports and genetic information. The goal is to avoid unnecessary surgery while ensuring the best outcomes.
This trial tests whether a combination of two immunotherapy drugs (nivolumab and relatlimab) can clear tiny amounts of cancer cells that remain after surgery in people with high-risk melanoma. It aims to prevent the cancer from coming back.
This study tests a new way to monitor people after surgery for early-stage melanoma. If you qualify, it may help your doctors watch for changes sooner or more accurately during follow-up.
This trial tests whether removing a clinically involved lymph node basin (via a specific lymph node excision surgery) after certain melanoma findings is helpful. It mainly aims to see effects on outcomes and on arm/leg swelling (lymphedema) after surgery.
This trial compares two surgeries for invasive melanoma: a narrow removal versus a wider one. It aims to see if a smaller surgery works as well, which could mean less scarring and recovery time.
Hear when a new Cutaneous Melanoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.