Surgery now versus radiation then delayed surgery for DCIS
Part of Cancer, Skin clinical trials.
This trial compares two approaches for ductal carcinoma in situ (DCIS): having surgery first versus getting radiation first and then having surgery later. It aims to see which plan controls DCIS better while affecting treatment timing and outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your biopsy shows DCIS only (not invasive cancer) on core needle biopsy
- The breast abnormality on imaging is 4 cm or less, and you don’t have a palpable lump
- You had a needle biopsy within 16 weeks before randomization, and a marker was placed for surgery/radiation planning
- Your planned surgery is usually lumpectomy (breast-conserving). Mastectomy may be allowed only in specific situations after randomization
- A radiation specialist believes partial breast radiation is feasible (about 30% or less of the breast volume)
- You can’t have had prior radiation to the same breast, and you can’t be pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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