Testing if a new test can guide radiation after lumpectomy for DCIS
Part of Cancer, Skin clinical trials.
This trial tests a new way to predict whether radiation after lumpectomy will help women with DCIS, a very early form of breast cancer. You'll take a test called DCISionRT that looks at your cancer's biology, then you'll be randomly assigned to either get radiation or not, so doctors can learn who really needs it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be a woman aged 30 to 85.
- You were diagnosed with DCIS (a very early, non-spreading breast cancer) within the last 4 months.
- You had a lumpectomy (breast-conserving surgery) and the edges of the removed tissue are clear of cancer (clean margins of at least 2 mm).
- Your DCIS must be 6 cm or smaller and have been tested for hormone receptors (ER/PR).
- You have not had prior breast cancer (DCIS or invasive) in either breast, and you have no suspicious areas left in the breast unless they were biopsied and found to be benign.
- You are healthy enough for daily activities (ECOG performance status 0-2) and have no conditions that prevent radiation therapy (like certain autoimmune diseases or prior chest radiation).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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