Clin2
NCT03955445Possibly a fitRecruiting

Study for long-term iptacopan in C3G or IC-MPGN

C3 GlomerulopathyImmune-complex-membranoproliferative Glomerulonephritis

Treatments studied

Part of Immune system & allergy, Kidney & urinary, Women’s health & pregnancy clinical trials.

This Phase 3 trial looks at how well and how safely iptacopan works over the long term for people with C3G or IC-MPGN. You may be able to join if you already finished a specific earlier study and you’re currently healthy enough for long-term treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
225 people
Ages
12 years to 100 years
Study type
Interventional

Who can take part

  • You finished the treatment period of the earlier CLNP023X2202, CLNP023B12301, or CLNP023B12302 study
  • You do not have a current infection (bacterial, viral, or fungal) within the last 14 days
  • You have not had a fever (38°C/100.4°F or higher) within the last 7 days
  • You do not have certain heart rhythm or heart electrical problems that raise safety risk
  • You do not have HIV or another condition that weakens your immune system

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07331259Not yet recruiting
A study of iptacopan for C3G patients

This trial tests a medicine called iptacopan for people with a kidney condition called C3G. It looks at how the disease progresses in those who have taken or are currently taking iptacopan.

NCT07416162Recruiting
Study of iptacopan for PNH or C3G in Korea

This trial tests a medicine called iptacopan for people with paroxysmal nocturnal hemoglobinuria (a rare blood disorder) or C3 glomerulopathy (a kidney disease). It aims to see if the drug is safe and effective for Korean patients.

Jeollanam
NCT06209736Recruiting· Phase 2
Study of OMS906 for C3G and ICGN kidney diseases

This study tests an experimental drug called OMS906 for people with C3G or ICGN (immune-related kidney diseases). It aims to see if the drug is safe and can reduce kidney damage. You may qualify if you have a confirmed diagnosis, high protein in your urine, and stable kidney function.

Kaunas
NCT04817618Recruiting· Phase 3
Iptacopan for kidney inflammation in C3 glomerulopathy

This trial studies whether iptacopan can improve outcomes and safety for people with C3 glomerulopathy, a kidney disease caused by overactive parts of the immune system. Participants must already be on standard kidney-protecting medicines and meet specific kidney function and urine protein criteria.

Aurora, Colorado
NCT06994845Recruiting· Phase 3
Testing iptacopan for children with IgA nephropathy

This study tests a new medicine called iptacopan to see if it helps children with IgA nephropathy (a kidney disease). Kids who join will receive the study treatment and be monitored for safety and effectiveness.

Aurora, Colorado
NCT07598448Not yet recruiting
Study of Iptacopan Treatment for C3G Patients in Spain

This study tracks adults with C3G (a rare kidney disease where the immune system damages the filtering units) who have already received iptacopan (a new medicine) through an early access program in Spain. Researchers want to understand how well this treatment works and its safety in real-world patients.

Hear when a new C3 Glomerulopathy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.