Test of a new plan for jaw reconstruction and implants
Part of Bones, joints & muscles, Cancer, Mouth & dental clinical trials.
This study checks whether the “O-bridge protocol” helps people who need jaw surgery—either for osteonecrosis of the jaw or for oral/jaw tumors—followed by dental implant placement to support fixed teeth (not removable dentures). The goal is to improve your ability to eat, speak, and get a stable tooth replacement plan after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of jaw osteonecrosis (ORN/MRONJ) OR a benign or cancerous tumor in the mouth/jaw bone that needs jaw resection (jaw bone surgery).
- Your treatment plan includes jaw/oral reconstruction plus dental implants that may be placed with immediate or delayed loading (teeth can be fixed using implants).
- You are not able to use a typical removable denture/partial denture solution to replace teeth.
- You must have no medical reason that makes jaw reconstruction with implant placement unsafe for you.
- If you need speech testing, you must be able to speak Dutch or English (other languages may be excluded from the speech part, though other speech clarity checks may still be done).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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