Clin2
NCT04016129Worth exploringNot yet recruiting

Car-t immunotherapy for cd19-negative leukemia

B-cell Leukemia

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests a new type of CAR-T therapy (a treatment that trains your immune cells to attack cancer) for people with certain types of B-cell leukemia that are CD19 negative or have relapsed after CD19 treatment. It may help if your cancer has other markers like CD22 or CD123.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
100 people
Ages
6 months to 75 years
Study type
Interventional

Who can take part

  • You must be older than 6 months.
  • Your cancer cells must be CD19 negative (meaning they don't have the CD19 marker) or have come back after a previous CD19 treatment.
  • Your cancer cells must have at least one of these markers: CD22, CD123, CD38, CD10, CD20, or TSLPR.
  • You must be in fairly good health (able to be up and about) and expected to live at least another month.
  • Your hemoglobin (a blood protein that carries oxygen) must be above 80 g/L.
  • You must not have major active infections (like HIV, hepatitis B or C) or be pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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