Test MRI to measure liver fat and NASH using biopsy
Part of Digestive system clinical trials.
This study checks whether an MRI scan can measure liver health in people with suspected fatty liver disease that may have progressed to NASH. Everyone in the study is also scheduled for a standard liver biopsy, which is used to compare the scan results.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You can understand the study and sign informed consent.
- You are suspected to have NAFLD and may be starting treatment, and you have at least two risk factors such as diabetes, high blood pressure, or high cholesterol/triglycerides.
- Your blood tests show elevated liver enzymes (ALT 40 or higher) OR you meet the study’s overall liver-risk profile described above.
- You are scheduled for a standard right-lobe liver biopsy (through the skin or through the neck).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at MRI scans to find better ways to diagnose NASH (a type of fatty liver disease with inflammation). If you are already scheduled for a liver biopsy for suspected NASH, an MRI might help researchers learn more about your condition.
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This study is looking for new ways to detect liver scarring (fibrosis) in people with fatty liver disease (NAFLD, NASH, MASLD, or MASH). If you qualify, you will give a blood sample to help identify biomarkers that could replace biopsies.
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This study aims to develop better ways to measure how much fibrosis (scarring) in the liver improves after treatment for NASH (fatty liver with inflammation). If you have moderate to severe liver scarring from NASH, this research could help doctors track your condition more precisely, which may lead to more effective care.
This study tests a new ultrasound device that uses sound waves to measure fat in the liver without needles or surgery. It is for people with a type of fatty liver disease called MASLD or MASH, who are already getting an MRI to check their liver.
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