TNF medication trial for blast-related tinnitus
Treatments studied
Part of Brain & nervous system, Ear, nose & throat clinical trials.
This Phase 2 study tests whether a TNF-α medicine can reduce tinnitus symptoms after blast or loud noise exposure, sometimes with traumatic brain injury. You may be a candidate if your tinnitus is at least moderately severe and stable over time, and if you meet other health and medication rules.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and can give written consent for the study
- Your tinnitus is at least moderately severe (Tinnitus Functional Index score 25 or higher)
- Your tinnitus started after blast/loud noise exposure or after a doctor-diagnosed concussion or traumatic brain injury
- Your tinnitus is constant (not coming and going) and not “pulsing”
- You must stop other tinnitus treatments or programs for 4 weeks before starting this study
- You must be able to do tinnitus questionnaires and hearing evaluations (or, if hearing loss is very severe, you can still rate how loud and upsetting it is)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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