Testing a new valve placed through a blood vessel
Part of Heart & circulation clinical trials.
This study checks whether an “investigational” transcatheter aortic valve is safe and works well for people with severe, calcified aortic stenosis (a stiff, narrowed heart valve). It may help improve valve function and symptoms, but you must meet specific heart, scan, and health-status requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 70 years or older and can provide informed consent
- Your heart ultrasound tests show calcified aortic stenosis (severe narrowing) by set numbers
- You feel symptoms from this valve problem (NYHA class II or higher)
- A CT scan shows your valve opening size is between 21 and 23 mm
- You are considered high risk for surgery (based on risk scores or your heart team’s judgment)
- You can travel for and agree to follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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