Test of DCB treatment to open new blocked heart arteries
Part of Heart & circulation clinical trials.
This trial studies a special artery treatment called DCB (drug-coated balloon) for new (de novo) blockages in people with coronary heart disease, guided by a heart scan measurement (QFR). It aims to check whether it is safe and works well to improve blood flow and reduce problems during follow-up.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have stable angina, unstable angina, or a recent heart attack, and the target blockage has QFR below 0.8
- You do not have a QFR below 0.8 outcome already ruled out by the study’s specific safety issues (like certain artery tearing or clotting after pre-dilation)
- Your heart pumping strength is not severely reduced (LVEF must be 30% or higher) and your breathing/heart-failure symptoms are not in the most severe class (NYHA III/IV)
- You do not have serious valve disease
- You can take the needed blood thinners used in this approach (aspirin and/or clopidogrel) without intolerance
- You are not allergic or unable to receive key medicines/materials used during the procedure (including heparin, contrast dye, and certain coating or drug-related materials)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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