Drug-coated balloon for coronary artery blockages
Part of Heart & circulation clinical trials.
This trial studies whether a drug-coated balloon can treat certain coronary artery narrowings in adults with chronic (long-term) coronary disease. It may help prevent re-narrowing after the procedure for people whose tests show the blockage is significant and needs treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older
- Have chronic coronary artery disease and be considered suitable for a stent/PCI procedure
- Have at least one significant new (de-novo) coronary blockage: more than 50% narrowed with flow test results (FFR or iFR within the trial’s limits) and an IVUS plan for a long drug-eluting stent (30 mm or longer)
- Not be having treatment for an acute coronary problem (like a heart attack or unstable chest pain)
- The blockage location must not be at the left main or certain artery openings (left circumflex or right coronary ostium)
- You must be able to safely receive adenosine (no key adenosine contraindications), and you are not pregnant/breast-feeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing a special balloon coated with medication to treat newly formed blockages in the heart's arteries. The medication may help keep the artery open after the balloon opens it during a standard procedure.
This trial tests a special balloon that releases medicine to open blocked heart arteries. It may help people with chest pain or silent ischemia by keeping arteries open longer.
This trial is studying a special balloon coated with a drug that helps keep heart arteries open after they are cleared. It might be an option for people with narrowed heart arteries who need a less invasive treatment.
This study looks at how well drug-coated balloons work in real life for people with coronary artery disease. These balloons deliver medicine to open blocked heart arteries, and this trial aims to see how they perform in different patients.
This trial tests a special balloon coated with a drug (sirolimus) to treat blockages in small heart arteries. If the balloon is successful, it may help keep the artery open without needing a permanent stent.
This study compares two kinds of drug-coated balloons used during angioplasty to open narrowed heart arteries in people with acute coronary syndrome. Both balloons slowly release medicine to help keep the artery open, and the trial aims to see if one works better than the other.
Hear when a new Chronic Coronary Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.