Comparing one- vs two-side brain stimulation for depression
Part of Mental health clinical trials.
This trial compares two versions of a noninvasive brain treatment called rTMS to see which side-to-side approach works better for major depression. You may be eligible if you still have moderate depressive symptoms despite trying at least one antidepressant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can freely and competently consent to join, and you’re 18 or older
- You have major depression (current episode) without psychosis, and it has not improved after at least one adequate antidepressant treatment this time
- Your depression is moderate right now (Hamilton Depression score of at least 15)
- You can read and speak English and/or French, and you’ve chosen to start the rTMS referral plan
- You can follow the treatment schedule, and your medication or therapy plan has been stable for at least 4 weeks
- If you’re 65 or older, your memory/thinking score on MMSE must be high enough (education-adjusted score at least 24)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether delivering a type of brain stimulation to the left side of the head is as effective as delivering it to the right side for treating major depression. The treatment is called transcranial magnetic stimulation (TMS), which uses magnetic pulses to stimulate brain areas involved in mood.
This study compares two types of repetitive transcranial magnetic stimulation (rTMS) to treat depression. One type uses a brain scan (fMRI) to guide the treatment, while the other uses a standard approach. It may help people whose depression hasn't improved with medication.
This trial compares two types of transcranial magnetic stimulation (TMS) to see which works better for people with depression. TMS uses magnetic pulses to stimulate brain areas involved in mood regulation.
This trial is for people with depression who have already gotten better after a 4-week course of theta burst stimulation (a type of brain stimulation). It tests two different schedules of ongoing brain stimulation (clustered vs. tapered) to see which helps prevent depression from coming back.
This study compares two early treatments for moderate-to-severe depression: repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, versus a standard antidepressant medication called escitalopram. The goal is to see which works better for people who have not yet tried antidepressants.
This trial tests if using brain imaging to guide the placement of transcranial magnetic stimulation (TMS) works better than the usual scalp-based targeting method for adults with treatment-resistant depression.
Hear when a new Major Depressive Episode trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.