Comparing two types of brain stimulation for depression
Part of Mental health clinical trials.
This trial tests if using brain imaging to guide the placement of transcranial magnetic stimulation (TMS) works better than the usual scalp-based targeting method for adults with treatment-resistant depression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 22 and 80 years old.
- You have been diagnosed with major depression and have moderate to severe treatment resistance.
- You score above 20 on two depression rating scales (Beck Depression Inventory and Montgomery-Åsberg Depression Rating Scale).
- You are on a stable antidepressant medication (or none) for 4 weeks before starting and agree not to change it during the study.
- You have a primary psychiatrist or therapist overseeing your care during the trial.
- You agree to avoid pregnancy, maintain your usual caffeine intake, and stop alcohol, tobacco, and drugs for 24 hours before each brain scan and treatment session.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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