Comparing two ways to target brain stimulation for depression
Part of Mental health clinical trials.
This study tests two methods of targeting repetitive transcranial magnetic stimulation (TMS) for depression: one using brain imaging to guide the treatment, and the other using a standard scalp measurement. The goal is to see if imaging-guided TMS works better for people with treatment-resistant depression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 22 and 80 years old.
- You have a diagnosis of major depressive disorder and score above 20 on two depression rating scales.
- Your depression has not improved enough with at least one prior treatment (moderate to severe treatment resistance).
- You have been on a stable antidepressant dose (or no medication) for at least 4 weeks before starting and agree to stay on that same dose during the study.
- You have a regular mental health provider (like a psychiatrist or therapist) who will continue to care for you during the trial.
- You agree to avoid pregnancy, limit caffeine, and avoid alcohol, tobacco, and recreational drugs before each treatment session.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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