PD-1 plus pyrotinib for HER2-mutated lung cancer after chemo
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a combination treatment—PD-1 plus pyrotinib—in people with advanced lung cancer that has a specific HER2 “insertion” genetic change. It may help if your first standard chemotherapy did not work and you still have measurable tumors to track.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced non-small cell lung cancer confirmed by a tissue or fluid test
- Your tumor has a HER2 insertion genetic mutation
- Your first standard chemotherapy did not control the cancer
- You have at least one measurable tumor spot that can be tracked on scans
- You have not previously taken PD-1 or pyrotinib (either one)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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