Closed-loop deep brain stimulation for long-lasting nerve pain
Part of Brain & nervous system, Injuries & trauma, Pain clinical trials.
This trial tests a “smart” deep brain stimulation device that senses your brain signals and adjusts treatment to reduce severe, long-lasting pain. It may help people whose pain has not improved with multiple pain medicines and surgery cannot fix the cause.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 22 to 80
- Have long-lasting (at least 2 years) severe pain that has not responded to typical treatments
- In the last 30 days, your pain score is usually above 6 out of 10 and varies by at least 3 points
- Have tried at least two different classes of pain medicines without enough relief (with stable doses for 30 days)
- Have no surgically fixable cause for the pain and meet the study’s pain-nerve “biomarker” or trial-stimulation response step, if done
- Be able to read/speak English, understand consent, and have no major memory/thinking problems (MoCA 25 or higher)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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