Test of chemotherapy plus your own stem cells for metastatic cancer
Treatments studied
Part of Cancer, Digestive system, Hormones & metabolism, Skin clinical trials.
This Phase 1 trial tests a treatment approach using standard chemotherapy along with stem cells taken from you to treat metastatic pancreatic or breast cancer. It is mainly designed to check safety and find the best way to give the treatment, and it may offer an option for people whose cancer has spread.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older.
- You have stage IV (advanced) pancreatic or breast cancer.
- You are expected to live at least 6 months, and other illnesses should not seriously limit your health.
- Your heart and organ function must be strong enough for study treatment (your care team will check this).
- You must not have had chemotherapy in the last 2 weeks.
- If you can become pregnant, you must use strict non-pill, non-injection birth control, or agree to true abstinence, during treatment and for 6 months after the last dose.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a method that analyzes your tumor's genes and grows a mini-tumor in a dish to find which drugs might work best for your metastatic pancreatic cancer. It aims to improve treatment choices by using these personalized tests.
This trial tests whether a blood test that detects tumor DNA can help doctors decide early if the standard chemotherapy is working, and if switching treatment might be better. It is for people newly diagnosed with metastatic pancreatic cancer who are starting their first chemotherapy.
This trial tests a new treatment using your own immune cells (called CAR-T cells) that are modified to target a protein called B7-H3 found on pancreatic cancer cells. The goal is to see if this therapy can help shrink or control the cancer.
This trial tests a new immunotherapy drug called ivonescimab combined with chemotherapy, with or without another experimental drug (AK117), for people with pancreatic cancer that has spread. The goal is to see if adding these therapies can help shrink tumors or slow the cancer's growth.
This trial tests an experimental cell therapy called MT-601 for people with advanced pancreatic cancer that has not worsened during standard chemotherapy (FOLFIRINOX or nab-paclitaxel/gemcitabine). The goal is to see if this new treatment can help control the cancer.
This trial is testing two immunotherapy drugs (balstilimab and botensilimab) to see if they can shrink tumors in people with advanced pancreatic cancer that has worsened after at least one prior treatment. If you have microsatellite stable (MSS) disease, you may be eligible.
Hear when a new BRCA1 Mutation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.