Appendicitis abscess treatment: drain surgery or antibiotics
Part of Digestive system, Infections clinical trials.
This study compares two ways to treat appendicitis that has formed an abscess or firm inflammatory mass (phlegmon) on a CT scan. It aims to see which approach works better and is safer for people with complicated appendicitis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your CT scan suggests complicated appendicitis with a possible perforation (a small tear) plus an abscess or phlegmon larger than 2 cm
- You have not taken antibiotics for more than 24 hours before being considered for the study
- You have not already had an attempt to drain the infection before joining the study
- You are not pregnant
- You do not have a serious antibiotic allergy that forces use of non-standard antibiotics instead of usual beta-lactams or quinolones
- You have not had major abdominal surgery through a large incision (laparotomy) before, and you have not been hospitalized in the last 2 weeks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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