Clinical trials
Appendicitis clinical trials
Below are recruiting appendicitis clinical trials, each written for real people, not researchers. We’re tracking 36 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06948071Recruiting
Enhanced recovery after surgery for complicated appendicitis
This study tests a special recovery program for people having laparoscopic surgery for a severe type of appendicitis. It aims to help you heal faster and leave the hospital sooner.
Los Angeles, CaliforniaAges 18 years+ - NCT07816029Recruiting
Closing a heart pouch to prevent stroke in atrial fibrillation
This study tests a device and procedure to close off a small pouch in the heart (left atrial appendage) where blood clots can form in people with atrial fibrillation. The goal is to reduce the risk of stroke, possibly lowering the need for long-term blood thinners.
PragueAges 18 years+ - NCT07521969Recruiting
Outpatient care after emergency appendix removal surgery
This trial tests whether patients with a specific type of appendix infection (gangrenous appendicitis) can safely recover at home instead of staying in the hospital after surgery. The goal is to see if home-based care with close follow-up visits works as well as traditional hospital stays.
Seville, SevillaAges 14 years+ - NCT07278869Recruiting
Study of Append system for atrial fibrillation patients
This trial tests a new device, the Append System, to close off the left atrial appendage (a small pouch in the heart) in people with atrial fibrillation. The goal is to reduce stroke risk without needing long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT07230379Recruiting
Comparing two treatments for first-time uncomplicated appendicitis
This trial tests a newer, less invasive procedure called ERAT against standard laparoscopic appendectomy for adults with a first episode of uncomplicated appendicitis. The goal is to see which approach works better with fewer risks.
Chongqing, ChingqingAges 18 years+ - NCT07008092Recruiting
Using PGE-M to predict appendicitis in children
This trial checks if a substance called PGE-M found in urine can help predict acute appendicitis in children with belly pain. If it works, it could help doctors diagnose appendicitis faster and without needing a blood test or CT scan.
SplitAges 5–17 - NCT06304285Recruiting
Acupuncture for Parkinson's with chronic appendicitis
This trial tests whether acupuncture can help people with Parkinson's disease who also have chronic appendicitis. It aims to see if treating the appendix inflammation may also improve Parkinson's symptoms.
Hefei, AnhuiAges 40–70 - NCT07640230Recruiting
Cartoons and games to ease surgery anxiety in children
This study tests whether watching cartoons or playing mobile games can help reduce anxiety and fear in children ages 7–12 who need surgery for appendicitis (an inflamed appendix). The goal is to find simple, non-medication ways to calm children before their operation.
AnkaraAges 7–12 - NCT07496723Recruiting
Comparing diagnostic methods for appendicitis surgery
This trial looks at whether different ways of diagnosing appendicitis (like CT scans) are accurate. It's for people who already had surgery to remove their appendix and want to help doctors learn more.
Sanliurfa, ŞanlıurfaAges 18 years+ - NCT07478029Recruiting
PEG bowel preparation study for appendectomy patients
This study tests if a bowel-cleaning solution (PEG) works well before colonoscopy. It compares people who have had their appendix removed to those who haven't.
Wuhan, HubeiAges 18–75 - NCT06774001Recruiting
Global study of appendectomy outcomes for appendicitis
This study follows people around the world who have their appendix removed for appendicitis. It aims to track outcomes and improve care for this common surgery.
CotonouAges Any age - NCT06841003RecruitingPhase 3
Antibiotic rinse during appendix surgery to prevent abscess
This trial tests whether rinsing the belly with antibiotics during appendix removal surgery can lower the chance of a pocket of infection (abscess) forming afterward. It may help people with a more severe type of appendicitis called complicated appendicitis.
Heerlen, LimburgAges 8 years+ - NCT06762275Recruiting
New way to diagnose appendicitis in children with belly pain
This study looks at a new way for general practitioners (GPs) to diagnose appendicitis in children with belly pain. It aims to find out if a special checklist or test can help GPs decide which children need to go to the hospital, potentially saving unnecessary trips.
Groningen, Provincie GroningenAges 4–18 - NCT06705842RecruitingPhase 4
Cost comparison study for burst appendix surgery
This study compares two different ways of managing care after surgery for a burst appendix (perforated appendicitis). It helps doctors understand which approach is more cost-effective and better for patients like you.
Houston, TexasAges 18 years+ - NCT04168866Recruiting
Appendicitis abscess treatment: drain surgery or antibiotics
This study compares two ways to treat appendicitis that has formed an abscess or firm inflammatory mass (phlegmon) on a CT scan. It aims to see which approach works better and is safer for people with complicated appendicitis.
New Haven, ConnecticutAges 18 years+ - NCT06395636Recruiting
Fitbit to detect infections after children's appendix surgery
This trial uses a Fitbit wearable to see if it can help detect infections early in children recovering from surgery for complicated appendicitis. It aims to improve recovery and catch problems sooner.
Chicago, IllinoisAges 3–18 - NCT06083064Recruiting
Smarter imaging choices for suspected appendicitis
This trial tests whether using a step-by-step approach to decide which imaging test (CT scan or ultrasound) is best for people with suspected appendicitis, instead of routinely giving everyone a CT scan or ultrasound. It may help avoid unnecessary scans.
EspooAges 18 years+ - NCT05761080RecruitingPhase 4
Faster recovery care for children with complicated appendicitis
This study tests a faster recovery plan for children who had surgery for complicated appendicitis. It aims to see if children can leave the hospital sooner and recover well at home with oral antibiotics instead of staying longer in the hospital.
Barcelona, BarcelonaAges 2–17 - NCT05075252Recruiting
Testing whether contamination level matters during laparoscopic appendicitis surgery
This study looks at appendicitis patients having laparoscopic surgery and tests whether the amount of contamination found during surgery affects outcomes. It may help surgeons choose the best way to clean the abdomen during the operation.
MilanAges 18–69 - NCT03234296Enrolling by invitation
Antibiotics versus placebo for uncomplicated appendicitis
This trial tests whether taking antibiotics alone can treat acute uncomplicated appendicitis, compared with a placebo. If antibiotics work, it may help some people avoid surgery or reduce treatment intensity.
TurkuAges 18–60 - NCT03643718Recruiting
Emergency surgery and trauma patient registry online
This trial is a web-based registry that collects information about people who need emergency surgical or non-surgical treatment for sudden (acute) problems. Your information can help doctors better understand and improve emergency care and decision-making.
PisaAges Any age - NCT06160778RecruitingPhase 3
Comparing two pain medicines for kids with belly pain
This study compares two common pain relievers—ketorolac and morphine—given through an IV to children with acute abdominal pain. It aims to find which works better and has fewer side effects for this condition.
Calgary, AlbertaAges 6–17 - NCT07824908Recruiting
Numbing medicine and pain after keyhole appendix removal
This study looks at whether the place where the appendix is taken out during keyhole surgery and the use of numbing medicine can help reduce pain after the operation. If you're having this emergency surgery, you may have less pain afterward.
Diyarbakır, KayapınarAges 18 years+ - NCT07794618Recruiting
Video review of safe appendix surgery for children
This study looks at videos of appendix removal surgery in children to see if they can help make surgery safer. If your child is having this surgery, the video may help doctors learn how to prevent problems.
Kayseri, KayseriAges 5–17
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Common questions
- Are there clinical trials for appendicitis?
- Yes. Clin2 currently lists 36 recruiting appendicitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a appendicitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a appendicitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.