Nelfinavir with chemo and radiation for vulvar cancer
Treatments studied
Part of Cancer, Women’s health & pregnancy clinical trials.
This Phase 1 trial tests whether adding nelfinavir to standard chemo (cisplatin) and external-beam radiation can treat locally advanced vulvar cancer that cannot be removed with surgery. It’s designed to check safety and how well the treatment can work for this situation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have vulvar cancer that has not been treated before and cannot be removed by surgery
- Your cancer stage is T2 to T4, and it may involve nearby lymph nodes (N0 to N3), but there is no spread to distant organs (M0)
- Your recent blood tests show enough white blood cells, platelets, kidney function, and acceptable liver test results
- You must be able to complete treatment and follow-up, and your overall condition is fair (ECOG/GOG 0–2)
- If you can become pregnant, you must use reliable birth control during the study, and you must be HIV-negative by blood test
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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