Clin2
NCT04214119Possibly a fitRecruiting

Capsule test during endoscopy to find early esophageal cancer

Barrett EsophagusEsophageal CancerGastric Cancer

Part of Cancer, Digestive system clinical trials.

This trial studies an “EsophaCap” capsule that can be swallowed during an endoscopy to help detect early esophageal cancer. It may help find cancer earlier and guide next steps, if your results are concerning.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
2,500 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years or older
  • You are scheduled for an upper endoscopy (esophagogastroduodenoscopy) at Johns Hopkins Hospital
  • You can safely swallow a capsule
  • You have not had an esophagus-removal surgery (esophagectomy)
  • You do not currently have an esophageal stent or a narrowing (stricture) that blocks the capsule
  • You have not had radiation to your chest

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06418516Not yet recruiting
Capsule sponge test to find esophagus cancer early

This trial tests a capsule sponge device to spot esophageal cancer in people at high risk, including those with past head or neck cancer or newly diagnosed esophageal cancer. The goal is to see if the capsule sponge can catch cancer early without needing a traditional endoscopy.

NCT05706025Enrolling by invitation
Testing a capsule to screen for Barrett’s and esophageal cancer

This study checks whether a swallowable capsule can help find signs of Barrett’s esophagus or esophageal cancer (or related risk) before or around an endoscopy. The goal is to see if this less invasive sampling method could improve screening.

Aurora, Colorado
NCT04561791Enrolling by invitation
Testing a swallowable scope for early detection of Barrett’s esophagus

This study checks whether a special swallowable “camera capsule” test done in primary care can find early warning changes called Barrett’s esophagus. If it works well, it could make screening easier for people at risk.

Boston, Massachusetts
NCT03961945Recruiting
Testing a new way to diagnose Barrett’s esophagus

This study tests minimally invasive, sample-based tests during an endoscopy to find Barrett’s esophagus and help sort it from esophageal cancer risk. It may help doctors spot changes earlier and more accurately using less invasive methods than standard tissue testing alone.

Scottsdale, Arizona
NCT06803927Recruiting
Detecting Barrett's esophagus with a non-endoscopic device

This trial tests a device that collects cells from the esophagus using a swallowed capsule, which may detect Barrett's esophagus without a standard endoscopy. It is for people who are already scheduled for an endoscopy.

Cordova, Tennessee
NCT07206589Not yet recruiting
New ways to screen for Barrett's esophagus

This trial tests two simple, non-surgical methods to look for Barrett's esophagus (a change in the lining of the swallowing tube) and early esophageal cancer. It is for people who are at higher risk or lower risk, but have never had Barrett's or cancer before.

Scottsdale, Arizona

Hear when a new Barrett Esophagus trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.