Gentle cell sampling to check for early signs of esophageal cancer
Part of Cancer, Digestive system clinical trials.
This study tests less invasive ways to detect high-grade dysplasia (very abnormal cells) and esophageal cancer in people with Barrett's esophagus, a condition that can increase cancer risk. It looks for these changes using cell samples taken during a routine endoscopy, which may be quicker and more comfortable than standard biopsies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 90 years old.
- You have been diagnosed with Barrett's esophagus with a segment of at least 1 centimeter seen during an endoscopy.
- A biopsy has shown changes in the cells (called intestinal metaplasia), with or without early abnormal cells (dysplasia).
- You are already scheduled for an endoscopy for routine care.
- You have not had treatments like photodynamic therapy, radiofrequency ablation, cryotherapy, or argon plasma coagulation for Barrett's esophagus (previous endoscopic mucosal resection is okay).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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